Melatonin exerts anti-oral cancer effect via suppressing LSD1 in patient-derived tumor xenograft models

Aberrant activation of histone lysine-specific demethylase (LSD1) increases tumorigenicity; hence, LSD1 is considered a therapeutic target for various human cancers. Although melatonin, an endogenously produced molecule, may defend against various cancers, the precise mechanism involved in its anti-...

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Detalles Bibliográficos
Autores principales: Yang, Cheng-Yu, Lin, Chih-Kung, Tsao, Chang-Huei, Hsieh, Cheng-Chih, Lin, Gu-Jiun, Ma, Kuo-Hsing, Shieh, Yi-Shing, Sytwu, Huey-Kang, Chen, Yuan-Wu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464909/
https://www.ncbi.nlm.nih.gov/pubmed/28422711
http://dx.doi.org/10.18632/oncotarget.16808

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464909/
https://www.ncbi.nlm.nih.gov/pubmed/28422711
http://dx.doi.org/10.18632/oncotarget.16808

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