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Prognostic value of EGFR and KRAS in circulating tumor DNA in patients with advanced non-small cell lung cancer: a systematic review and meta-analysis

EGFR (exon 19 and exon 21) mutations in patients with advanced non-small cell lung cancer (NSCLC) treated by EGFR-TKIs are associated with a better survival; while KRAS mutations predict a worse prognosis. However, there are divergent findings regarding the prognostic value of EGFR and KRAS mutation...

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Detalles Bibliográficos
Autores principales: Fan, Gaowei, Zhang, Kuo, Ding, Jiansheng, Li, Jinming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464923/
https://www.ncbi.nlm.nih.gov/pubmed/28430611
http://dx.doi.org/10.18632/oncotarget.15412