Cargando…
αB-crystallin is a sensor for assembly intermediates and for the subunit topology of desmin intermediate filaments
Mutations in the small heat shock protein chaperone CRYAB (αB-crystallin/HSPB5) and the intermediate filament protein desmin, phenocopy each other causing cardiomyopathies. Whilst the binding sites for desmin on CRYAB have been determined, desmin epitopes responsible for CRYAB binding and also the p...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5465037/ https://www.ncbi.nlm.nih.gov/pubmed/28470624 http://dx.doi.org/10.1007/s12192-017-0788-7 |