αB-crystallin is a sensor for assembly intermediates and for the subunit topology of desmin intermediate filaments

Mutations in the small heat shock protein chaperone CRYAB (αB-crystallin/HSPB5) and the intermediate filament protein desmin, phenocopy each other causing cardiomyopathies. Whilst the binding sites for desmin on CRYAB have been determined, desmin epitopes responsible for CRYAB binding and also the p...

Descripción completa

Detalles Bibliográficos
Autores principales: Sharma, Sarika, Conover, Gloria M., Elliott, Jayne L., Der Perng, Ming, Herrmann, Harald, Quinlan, Roy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2017
Materias:
Small Heat Shock Proteins
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5465037/
https://www.ncbi.nlm.nih.gov/pubmed/28470624
http://dx.doi.org/10.1007/s12192-017-0788-7

Ejemplares similares

Ejemplares similares