Hematopoietic Id Deletion Triggers Endomyocardial Fibrotic and Vascular Defects in the Adult Heart

Inhibitor of DNA binding (Id) proteins play important roles in regulating cardiac development via paracrine signaling. Id1/Id3 knockout mice die at mid-gestation with multiple cardiac defects. Single Id knockout studies have not reported cardiomyopathies. To bypass embryonic lethality we used Tie2CR...

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Detalles Bibliográficos
Autores principales: Chang, Corey, Zhao, Qingshi, Gonzalez, J. Patrick, Kim, Jung H., Alzahrani, Kamal, Del Re, Dominic, Fraidenraich, Diego
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5465087/
https://www.ncbi.nlm.nih.gov/pubmed/28596553
http://dx.doi.org/10.1038/s41598-017-03160-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5465087/
https://www.ncbi.nlm.nih.gov/pubmed/28596553
http://dx.doi.org/10.1038/s41598-017-03160-7

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