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RCAN-11R peptide provides immunosuppression for fully mismatched islet allografts in mice

Calcineurin inhibitors have been used for transplant therapy. However, the inhibition of calcineurin outside the immune system has a number of side effects. We previously developed a cell-permeable inhibitor of NFAT (nuclear factor of activated T cells) using the polyarginine peptide delivery system...

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Detalles Bibliográficos
Autores principales: Noguchi, Hirofumi, Sugimoto, Koji, Miyagi-Shiohira, Chika, Nakashima, Yoshiki, Kobayashi, Naoya, Saitoh, Issei, Watanabe, Masami, Noguchi, Yasufumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5465209/
https://www.ncbi.nlm.nih.gov/pubmed/28596584
http://dx.doi.org/10.1038/s41598-017-02934-3

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