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RCAN-11R peptide provides immunosuppression for fully mismatched islet allografts in mice
Calcineurin inhibitors have been used for transplant therapy. However, the inhibition of calcineurin outside the immune system has a number of side effects. We previously developed a cell-permeable inhibitor of NFAT (nuclear factor of activated T cells) using the polyarginine peptide delivery system...
Autores principales: | Noguchi, Hirofumi, Sugimoto, Koji, Miyagi-Shiohira, Chika, Nakashima, Yoshiki, Kobayashi, Naoya, Saitoh, Issei, Watanabe, Masami, Noguchi, Yasufumi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5465209/ https://www.ncbi.nlm.nih.gov/pubmed/28596584 http://dx.doi.org/10.1038/s41598-017-02934-3 |
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