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A Combination of Podophyllotoxin and Rutin Alleviates Radiation-Induced Pneumonitis and Fibrosis through Modulation of Lung Inflammation in Mice

Pneumonitis and pulmonary fibrosis are predominant consequences of radiation exposure, whether planned or accidental. The present study, demonstrates radioprotective potential of a formulation, prepared by combining podophyllotoxin and rutin (G-003M), in mice exposed to 11 Gy thoracic gamma radiatio...

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Detalles Bibliográficos
Autores principales: Verma, Savita, Kalita, Bhargab, Bajaj, Sania, Prakash, Hridayesh, Singh, Ajay Kumar, Gupta, Manju Lata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5465247/
https://www.ncbi.nlm.nih.gov/pubmed/28649248
http://dx.doi.org/10.3389/fimmu.2017.00658

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