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Enantioselective decarboxylative chlorination of β-ketocarboxylic acids

Stereoselective halogenation is a highly useful organic transformation for multistep syntheses because the resulting chiral organohalides can serve as precursors for various medicinally relevant derivatives. Even though decarboxylative halogenation of aliphatic carboxylic acids is a useful and funda...

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Detalles Bibliográficos
Autores principales: Shibatomi, Kazutaka, Kitahara, Kazumasa, Sasaki, Nozomi, Kawasaki, Yohei, Fujisawa, Ikuhide, Iwasa, Seiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5465354/
https://www.ncbi.nlm.nih.gov/pubmed/28580951
http://dx.doi.org/10.1038/ncomms15600