Alert Regarding Cisplatin-induced Severe Adverse Events in Cancer Patients with Xeroderma Pigmentosum

Xeroderma pigmentosum (XP) is a genetic disease in which DNA repair mechanisms are impaired. Cisplatin (CDDP) exerts cytotoxic effects by forming mainly intrastrand DNA cross-links, and sensitivity to CDDP depends on the DNA repair system. Several in vitro studies have suggested that treatment with...

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Detalles Bibliográficos
Autores principales: Sumiyoshi, Makoto, Soda, Hiroshi, Sadanaga, Noriaki, Taniguchi, Hirokazu, Ikeda, Takaya, Maruta, Hiroshi, Dotsu, Yosuke, Ogawara, Daiki, Fukuda, Yuichi, Mukae, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5465418/
https://www.ncbi.nlm.nih.gov/pubmed/28420850
http://dx.doi.org/10.2169/internalmedicine.56.7866

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5465418/
https://www.ncbi.nlm.nih.gov/pubmed/28420850
http://dx.doi.org/10.2169/internalmedicine.56.7866

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