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Exosome miR-371b-5p promotes proliferation of lung alveolar progenitor type II cells by using PTEN to orchestrate the PI3K/Akt signaling

BACKGROUND: Pathways directing endogenous stem/progenitor cells to restore normal architecture and function of damaged/diseased lungs remain underexplored. Published data have revealed that alveolar progenitor type II cell (ATIIC)-derived signaling promotes re-epithelialization of injured alveoli, y...

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Detalles Bibliográficos
Autores principales: Quan, Yuan, Wang, Zhaohua, Gong, Ling, Peng, Xinmiao, Richard, Melissa A., Zhang, Junlan, Fornage, Myriam, Alcorn, Joseph L., Wang, Dachun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5465462/
https://www.ncbi.nlm.nih.gov/pubmed/28595637
http://dx.doi.org/10.1186/s13287-017-0586-2