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Effects of altered sialic acid biosynthesis on N-linked glycan branching and cell surface interactions

GNE (UDP-GlcNAc 2-epimerase/ManNAc kinase) myopathy is a rare muscle disorder associated with aging and is related to sporadic inclusion body myositis, the most common acquired muscle disease of aging. Although the cause of sporadic inclusion body myositis is unknown, GNE myopathy is associated with...

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Detalles Bibliográficos
Autores principales: Pham, Nam D., Pang, Poh-Choo, Krishnamurthy, Soumya, Wands, Amberlyn M., Grassi, Paola, Dell, Anne, Haslam, Stuart M., Kohler, Jennifer J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5465488/
https://www.ncbi.nlm.nih.gov/pubmed/28424265
http://dx.doi.org/10.1074/jbc.M116.764597

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