Development of an objective gene expression panel as an alternative to self-reported symptom scores in human influenza challenge trials

BACKGROUND: Influenza challenge trials are important for vaccine efficacy testing. Currently, disease severity is determined by self-reported scores to a list of symptoms which can be highly subjective. A more objective measure would allow for improved data analysis. METHODS: Twenty-one volunteers p...

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Detalles Bibliográficos
Autores principales: Muller, Julius, Parizotto, Eneida, Antrobus, Richard, Francis, James, Bunce, Campbell, Stranks, Amanda, Nichols, Marshall, McClain, Micah, Hill, Adrian V. S., Ramasamy, Adaikalavan, Gilbert, Sarah C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5465537/
https://www.ncbi.nlm.nih.gov/pubmed/28595644
http://dx.doi.org/10.1186/s12967-017-1235-3

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