SIX3, a tumor suppressor, inhibits astrocytoma tumorigenesis by transcriptional repression of AURKA/B

BACKGROUND: SIX homeobox 3 (SIX3) is a member of the sine oculis homeobox transcription factor family. It plays a vital role in the nervous system development. Our previous study showed that the SIX3 gene is hypermethylated, and its expression is decreased in astrocytoma, but the role of SIX3 remain...

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Detalles Bibliográficos
Autores principales: Yu, Zhibin, Sun, Yingnan, She, Xiaoling, Wang, Zeyou, Chen, Shuai, Deng, Zhiyong, Zhang, Yan, Liu, Qiang, Liu, Qing, Zhao, Chunhua, Li, Peiyao, Liu, Changhong, Feng, Jianbo, Fu, Haijuan, Li, Guiyuan, Wu, Minghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5465582/
https://www.ncbi.nlm.nih.gov/pubmed/28595628
http://dx.doi.org/10.1186/s13045-017-0483-2

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