Cargando…
Cytokine treatment optimises the immunotherapeutic effects of umbilical cord-derived MSC for treatment of inflammatory liver disease
BACKGROUND: Mesenchymal stromal cells (MSC) possess immunomodulatory properties and low immunogenicity, both crucial properties for their development into an effective cellular immunotherapy. They have shown benefit in clinical trials targeting liver diseases; however the efficacy of MSC therapy wil...
Autores principales: | de Witte, Samantha F. H., Merino, Ana M., Franquesa, Marcella, Strini, Tanja, van Zoggel, Johanna A. A., Korevaar, Sander S., Luk, Franka, Gargesha, Madhu, O’Flynn, Lisa, Roy, Debashish, Elliman, Steve J., Newsome, Philip N., Baan, Carla C., Hoogduijn, Martin J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5465593/ https://www.ncbi.nlm.nih.gov/pubmed/28595619 http://dx.doi.org/10.1186/s13287-017-0590-6 |
Ejemplares similares
-
Inflammatory Conditions Dictate the Effect of Mesenchymal Stem or Stromal Cells on B Cell Function
por: Luk, Franka, et al.
Publicado: (2017) -
Toward Development of iMesenchymal Stem Cells for Immunomodulatory Therapy
por: de Witte, Samantha F. H., et al.
Publicado: (2016) -
Update on Controls for Isolation and Quantification Methodology of Extracellular Vesicles Derived from Adipose Tissue Mesenchymal Stem Cells
por: Franquesa, Marcella, et al.
Publicado: (2014) -
Membrane particles generated from mesenchymal stromal cells modulate immune responses by selective targeting of pro-inflammatory monocytes
por: Gonçalves, Fabiany da C., et al.
Publicado: (2017) -
Administration of Human MSC-Derived Extracellular Vesicles for the Treatment of Primary Sclerosing Cholangitis: Preclinical Data in MDR2 Knockout Mice
por: Angioni, Roberta, et al.
Publicado: (2020)