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Blood flow velocity and thickness of the choroid in a patient with chorioretinopathy associated with ocular blunt trauma

BACKGROUND: Choroidal circulation hemodynamics in eyes with ocular blunt trauma has not been quantitatively examined yet. We quantitatively examined changes in choroidal blood flow velocity and thickness at the lesion site using laser speckle flowgraphy (LSFG) and enhanced depth imaging optical cohe...

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Autores principales: Ishikawa, Yuri, Hashimoto, Yuki, Saito, Wataru, Ando, Ryo, Ishida, Susumu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5465595/
https://www.ncbi.nlm.nih.gov/pubmed/28595625
http://dx.doi.org/10.1186/s12886-017-0480-9
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author Ishikawa, Yuri
Hashimoto, Yuki
Saito, Wataru
Ando, Ryo
Ishida, Susumu
author_facet Ishikawa, Yuri
Hashimoto, Yuki
Saito, Wataru
Ando, Ryo
Ishida, Susumu
author_sort Ishikawa, Yuri
collection PubMed
description BACKGROUND: Choroidal circulation hemodynamics in eyes with ocular blunt trauma has not been quantitatively examined yet. We quantitatively examined changes in choroidal blood flow velocity and thickness at the lesion site using laser speckle flowgraphy (LSFG) and enhanced depth imaging optical coherence tomography (EDI-OCT) in a patient with chorioretinopathy associated with ocular blunt trauma. CASE PRESENTATION: A 13-year-old boy developed a chorioretinal lesion with pigmentation extending from the optic disc to the superotemporal side in the right eye after ocular blunt trauma. The patient’s best-corrected visual acuity (BCVA) was 0.2 in the right eye. Indocyanine green angiography showed hypofluorescence from the initial phase, with a decrease of mean blur rate (MBR) on LSFG color map, which corresponded to the chorioretinal lesion. The BCVA and foveal outer retinal morphologic abnormality spontaneously improved during follow-up. MBR and choroidal thickness increased by 23–31% and 13–17 μm at the lesion site and by 11–22% and 33–42 μm at the fovea, respectively, during the 6-month follow-up period after baseline measurements in the affected eye. In contrast, these parameters showed little or no changes at the normal retinal site in the affected eye and the fovea in the fellow eye. CONCLUSIONS: Current data revealed that both blood flow velocity and thickness in the choroid at the lesion site decreased in the acute stage and subsequently increased together with improvements in visual function and outer retinal morphology. These results suggest that LSFG and EDI-OCT may be useful indices that can noninvasively evaluate activity of choroidal involvement in ocular blunt trauma-associated chorioretinopathy.
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spelling pubmed-54655952017-06-09 Blood flow velocity and thickness of the choroid in a patient with chorioretinopathy associated with ocular blunt trauma Ishikawa, Yuri Hashimoto, Yuki Saito, Wataru Ando, Ryo Ishida, Susumu BMC Ophthalmol Case Report BACKGROUND: Choroidal circulation hemodynamics in eyes with ocular blunt trauma has not been quantitatively examined yet. We quantitatively examined changes in choroidal blood flow velocity and thickness at the lesion site using laser speckle flowgraphy (LSFG) and enhanced depth imaging optical coherence tomography (EDI-OCT) in a patient with chorioretinopathy associated with ocular blunt trauma. CASE PRESENTATION: A 13-year-old boy developed a chorioretinal lesion with pigmentation extending from the optic disc to the superotemporal side in the right eye after ocular blunt trauma. The patient’s best-corrected visual acuity (BCVA) was 0.2 in the right eye. Indocyanine green angiography showed hypofluorescence from the initial phase, with a decrease of mean blur rate (MBR) on LSFG color map, which corresponded to the chorioretinal lesion. The BCVA and foveal outer retinal morphologic abnormality spontaneously improved during follow-up. MBR and choroidal thickness increased by 23–31% and 13–17 μm at the lesion site and by 11–22% and 33–42 μm at the fovea, respectively, during the 6-month follow-up period after baseline measurements in the affected eye. In contrast, these parameters showed little or no changes at the normal retinal site in the affected eye and the fovea in the fellow eye. CONCLUSIONS: Current data revealed that both blood flow velocity and thickness in the choroid at the lesion site decreased in the acute stage and subsequently increased together with improvements in visual function and outer retinal morphology. These results suggest that LSFG and EDI-OCT may be useful indices that can noninvasively evaluate activity of choroidal involvement in ocular blunt trauma-associated chorioretinopathy. BioMed Central 2017-06-08 /pmc/articles/PMC5465595/ /pubmed/28595625 http://dx.doi.org/10.1186/s12886-017-0480-9 Text en © The Author(s). 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Ishikawa, Yuri
Hashimoto, Yuki
Saito, Wataru
Ando, Ryo
Ishida, Susumu
Blood flow velocity and thickness of the choroid in a patient with chorioretinopathy associated with ocular blunt trauma
title Blood flow velocity and thickness of the choroid in a patient with chorioretinopathy associated with ocular blunt trauma
title_full Blood flow velocity and thickness of the choroid in a patient with chorioretinopathy associated with ocular blunt trauma
title_fullStr Blood flow velocity and thickness of the choroid in a patient with chorioretinopathy associated with ocular blunt trauma
title_full_unstemmed Blood flow velocity and thickness of the choroid in a patient with chorioretinopathy associated with ocular blunt trauma
title_short Blood flow velocity and thickness of the choroid in a patient with chorioretinopathy associated with ocular blunt trauma
title_sort blood flow velocity and thickness of the choroid in a patient with chorioretinopathy associated with ocular blunt trauma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5465595/
https://www.ncbi.nlm.nih.gov/pubmed/28595625
http://dx.doi.org/10.1186/s12886-017-0480-9
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