Difference in Neutropenia due to Administration Schedule of TAS-102

TAS-102 significantly improves overall survival in patients with metastatic colorectal cancer. The most common adverse event of TAS-102 is bone marrow suppression, which leads to neutropenia. The incidence of neutropenia is high, and there is no known effective prevention method. Furthermore, the ad...

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Detalles Bibliográficos
Autores principales: Yoshida, Yoichiro, Aisu, Naoya, Mogi, Ai, Komono, Akira, Sakamoto, Ryohei, Kojima, Daibo, Mera, Toshiyuki, Hasegawa, Suguru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5465677/
https://www.ncbi.nlm.nih.gov/pubmed/28611635
http://dx.doi.org/10.1159/000460242
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author Yoshida, Yoichiro
Aisu, Naoya
Mogi, Ai
Komono, Akira
Sakamoto, Ryohei
Kojima, Daibo
Mera, Toshiyuki
Hasegawa, Suguru
author_facet Yoshida, Yoichiro
Aisu, Naoya
Mogi, Ai
Komono, Akira
Sakamoto, Ryohei
Kojima, Daibo
Mera, Toshiyuki
Hasegawa, Suguru
author_sort Yoshida, Yoichiro
collection PubMed
description TAS-102 significantly improves overall survival in patients with metastatic colorectal cancer. The most common adverse event of TAS-102 is bone marrow suppression, which leads to neutropenia. The incidence of neutropenia is high, and there is no known effective prevention method. Furthermore, the administration method of TAS-102 is complicated. We reported that neutropenia could be avoided by changing to a simple administration method of TAS-102.
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spelling pubmed-54656772017-06-13 Difference in Neutropenia due to Administration Schedule of TAS-102 Yoshida, Yoichiro Aisu, Naoya Mogi, Ai Komono, Akira Sakamoto, Ryohei Kojima, Daibo Mera, Toshiyuki Hasegawa, Suguru Case Rep Oncol Case Report TAS-102 significantly improves overall survival in patients with metastatic colorectal cancer. The most common adverse event of TAS-102 is bone marrow suppression, which leads to neutropenia. The incidence of neutropenia is high, and there is no known effective prevention method. Furthermore, the administration method of TAS-102 is complicated. We reported that neutropenia could be avoided by changing to a simple administration method of TAS-102. S. Karger AG 2017-03-02 /pmc/articles/PMC5465677/ /pubmed/28611635 http://dx.doi.org/10.1159/000460242 Text en Copyright © 2017 by The Author(s)Published by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/4.0/ This article is licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission.
spellingShingle Case Report
Yoshida, Yoichiro
Aisu, Naoya
Mogi, Ai
Komono, Akira
Sakamoto, Ryohei
Kojima, Daibo
Mera, Toshiyuki
Hasegawa, Suguru
Difference in Neutropenia due to Administration Schedule of TAS-102
title Difference in Neutropenia due to Administration Schedule of TAS-102
title_full Difference in Neutropenia due to Administration Schedule of TAS-102
title_fullStr Difference in Neutropenia due to Administration Schedule of TAS-102
title_full_unstemmed Difference in Neutropenia due to Administration Schedule of TAS-102
title_short Difference in Neutropenia due to Administration Schedule of TAS-102
title_sort difference in neutropenia due to administration schedule of tas-102
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5465677/
https://www.ncbi.nlm.nih.gov/pubmed/28611635
http://dx.doi.org/10.1159/000460242
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