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Necroptosis Execution Is Mediated by Plasma Membrane Nanopores Independent of Calcium

Necroptosis is a form of regulated necrosis that results in cell death and content release after plasma membrane permeabilization. However, little is known about the molecular events responsible for the disruption of the plasma membrane. Here, we find that early increase in cytosolic calcium in TNF-...

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Detalles Bibliográficos
Autores principales: Ros, Uris, Peña-Blanco, Aida, Hänggi, Kay, Kunzendorf, Ulrich, Krautwald, Stefan, Wong, W. Wei-Lynn, García-Sáez, Ana J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5465952/
https://www.ncbi.nlm.nih.gov/pubmed/28380356
http://dx.doi.org/10.1016/j.celrep.2017.03.024