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Determination of Ion Atmosphere Effects on the Nucleic Acid Electrostatic Potential and Ligand Association Using AH(+)·C Wobble Formation in Double-Stranded DNA
[Image: see text] The high charge density of nucleic acids and resulting ion atmosphere profoundly influence the conformational landscape of RNA and DNA and their association with small molecules and proteins. Electrostatic theories have been applied to quantitatively model the electrostatic potenti...
Autores principales: | Allred, Benjamin E., Gebala, Magdalena, Herschlag, Daniel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2017
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466006/ https://www.ncbi.nlm.nih.gov/pubmed/28489947 http://dx.doi.org/10.1021/jacs.7b01830 |
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