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Methodological Rigor in Preclinical Cardiovascular Studies: Targets to Enhance Reproducibility and Promote Research Translation
RATIONALE: Methodological sources of bias and suboptimal reporting contribute to irreproducibility in preclinical science and may negatively affect research translation. Randomization, blinding, sample size estimation, and considering sex as a biological variable are deemed crucial study design elem...
Autores principales: | Ramirez, F. Daniel, Motazedian, Pouya, Jung, Richard G., Di Santo, Pietro, MacDonald, Zachary D., Moreland, Robert, Simard, Trevor, Clancy, Aisling A., Russo, Juan J., Welch, Vivian A., Wells, George A., Hibbert, Benjamin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466021/ https://www.ncbi.nlm.nih.gov/pubmed/28373349 http://dx.doi.org/10.1161/CIRCRESAHA.117.310628 |
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