Multicomponent mixtures for cryoprotection and ligand solubilization()

Mixed cryoprotectants have been developed for the solubilization of ligands for crystallization of protein–ligand complexes and for crystal soaking. Low affinity lead compounds with poor solubility are problematic for structural studies. Complete ligand solubilization is required for co-crystallizat...

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Detalles Bibliográficos
Autores principales: Ciccone, Lidia, Vera, Laura, Tepshi, Livia, Rosalia, Lea, Rossello, Armando, Stura, Enrico A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466044/
https://www.ncbi.nlm.nih.gov/pubmed/28626721
http://dx.doi.org/10.1016/j.btre.2015.05.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466044/
https://www.ncbi.nlm.nih.gov/pubmed/28626721
http://dx.doi.org/10.1016/j.btre.2015.05.008

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