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Soluble klotho may be a marker of phosphate reabsorption

Background: Membrane-bound α-klotho functions as a co-receptor with fibroblast growth factor receptor at the renal tubule conferring specificity to fibroblast growth factor-23 (FGF-23), allowing it to inhibit tubular phosphate reabsorption at physiological concentrations. α-klotho also exists as a s...

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Detalles Bibliográficos
Autores principales: Tan, Sven-Jean, Smith, Edward R., Holt, Stephen G., Hewitson, Tim D., Toussaint, Nigel D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466110/
https://www.ncbi.nlm.nih.gov/pubmed/28616218
http://dx.doi.org/10.1093/ckj/sfw146

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