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Development of fed-batch profiles for efficient biosynthesis of catechol-O-methyltransferase

Catechol-O-methyltransferase (COMT, EC 2.1.1.6) plays a crucial role in dopamine metabolism which has intimately linked this enzyme to some neurodegenerative diseases, such as Parkinson's disease. In recent years, in the attempt of developing new therapeutic strategies for Parkinson's dise...

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Detalles Bibliográficos
Autores principales:	Espírito Santo, G.M., Pedro, A.Q., Oppolzer, D., Bonifácio, M.J., Queiroz, J.A., Silva, F., Passarinha, L.A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466112/ https://www.ncbi.nlm.nih.gov/pubmed/28626646 http://dx.doi.org/10.1016/j.btre.2014.05.005

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