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Proliferation extent of CD34(+) cells as a key parameter to maximize megakaryocytic differentiation of umbilical cord blood-derived hematopoietic stem/progenitor cells in a two-stage culture protocol()
Co-infusion of ex-vivo generated megakaryocytic progenitors with hematopoietic stem/progenitor cells (HSC/HPC) may contribute to a faster platelet recovery upon umbilical cord blood (UCB) transplantation. A two stage protocol containing cell expansion and megakaryocyte (Mk) differentiation was estab...
Autores principales: | Hatami, Javad, Andrade, Pedro Z., Bacalhau, Denise, Cirurgião, Fernando, Ferreira, Frederico Castelo, Cabral, Joaquim M.S., da Silva, Cláudia L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466120/ https://www.ncbi.nlm.nih.gov/pubmed/28626662 http://dx.doi.org/10.1016/j.btre.2014.07.002 |
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