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Improving the biophysical properties of anti-ricin single-domain antibodies()
Single-domain antibodies (sdAbs) derived from heavy-chain only antibodies produced in camelids are attractive immunoreagents due to their small size, high affinity, and ability to refold and retain binding activity after denaturation. It has been observed that some sdAbs, however, exhibit undesirabl...
Autores principales: | Turner, Kendrick B., Liu, Jinny L., Zabetakis, Dan, Lee, Audrey Brozozog, Anderson, George P., Goldman, Ellen R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466252/ https://www.ncbi.nlm.nih.gov/pubmed/28626694 http://dx.doi.org/10.1016/j.btre.2015.01.001 |
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