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Improving the biophysical properties of anti-ricin single-domain antibodies()

Single-domain antibodies (sdAbs) derived from heavy-chain only antibodies produced in camelids are attractive immunoreagents due to their small size, high affinity, and ability to refold and retain binding activity after denaturation. It has been observed that some sdAbs, however, exhibit undesirabl...

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Detalles Bibliográficos
Autores principales: Turner, Kendrick B., Liu, Jinny L., Zabetakis, Dan, Lee, Audrey Brozozog, Anderson, George P., Goldman, Ellen R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466252/
https://www.ncbi.nlm.nih.gov/pubmed/28626694
http://dx.doi.org/10.1016/j.btre.2015.01.001

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