Vaccination with a Leishmania infantum HSP70-II null mutant confers long-term protective immunity against Leishmania major infection in two mice models

BACKGROUND: The immunization with genetically attenuated Leishmania cell lines has been associated to the induction of memory and effector T cell responses against Leishmania able to control subsequent challenges. A Leishmania infantum null mutant for the HSP70-II genes has been described, possessin...

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Detalles Bibliográficos
Autores principales: Solana, José Carlos, Ramírez, Laura, Corvo, Laura, de Oliveira, Camila Indiani, Barral-Netto, Manoel, Requena, José María, Iborra, Salvador, Soto, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466331/
https://www.ncbi.nlm.nih.gov/pubmed/28558043
http://dx.doi.org/10.1371/journal.pntd.0005644

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