MicroRNA 26a (miR-26a)/KLF4 and CREB-C/EBPβ regulate innate immune signaling, the polarization of macrophages and the trafficking of Mycobacterium tuberculosis to lysosomes during infection

For efficient clearance of Mycobacterium tuberculosis (Mtb), macrophages tilt towards M1 polarization leading to the activation of transcription factors associated with the production of antibacterial effector molecules such as nitric oxide (NO) and proinflammatory cytokines such as interleukin 1 β...

Descripción completa

Detalles Bibliográficos
Autores principales: Sahu, Sanjaya Kumar, Kumar, Manish, Chakraborty, Sohini, Banerjee, Srijon Kaushik, Kumar, Ranjeet, Gupta, Pushpa, Jana, Kuladip, Gupta, Umesh D., Ghosh, Zhumur, Kundu, Manikuntala, Basu, Joyoti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466338/
https://www.ncbi.nlm.nih.gov/pubmed/28558034
http://dx.doi.org/10.1371/journal.ppat.1006410

Ejemplares similares

Ejemplares similares