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Silencing of AQP3 induces apoptosis of gastric cancer cells via downregulation of glycerol intake and downstream inhibition of lipogenesis and autophagy

Gastric cancer (GC) has a poor prognosis and is a leading cause of cancer-related death. Optimal therapeutic targets have not been identified. AQP3 is capable of transporting glycerol across the cytomembrane. Previous studies have shown that AQP3 is involved in proliferation, invasion and migration...

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Detalles Bibliográficos
Autores principales: Chen, Liang, Li, Zheng, Zhang, Qiang, Wei, Song, Li, Bowen, Zhang, Xuan, Zhang, Lei, Li, Qing, Xu, Hao, Xu, Zekuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466363/
https://www.ncbi.nlm.nih.gov/pubmed/28620264
http://dx.doi.org/10.2147/OTT.S134016

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