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A case of pancreatic schwannoma showing increased FDG uptake on PET/CT

INTRODUCTION: Schwannomas are neoplasms originating from Schwann cells in nerve sheath, but pancreatic schwannomas are rare. PRESENTATION OF CASE: A 59-year-old female incidentally pointed out a 2-cm-sized solid mass in the pancreas head by computed tomography (CT) which was performed for other reas...

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Autores principales: Fukuhara, Sotaro, Fukuda, Saburo, Tazawa, Hirofumi, Imaoka, Kouki, Mochizuki, Tetsuya, Hirata, Yuzo, Fujisaki, Seiji, Takahashi, Mamoru, Nishida, Toshihiro, Sakimoto, Hideto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466559/
https://www.ncbi.nlm.nih.gov/pubmed/28599230
http://dx.doi.org/10.1016/j.ijscr.2017.05.031
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author Fukuhara, Sotaro
Fukuda, Saburo
Tazawa, Hirofumi
Imaoka, Kouki
Mochizuki, Tetsuya
Hirata, Yuzo
Fujisaki, Seiji
Takahashi, Mamoru
Nishida, Toshihiro
Sakimoto, Hideto
author_facet Fukuhara, Sotaro
Fukuda, Saburo
Tazawa, Hirofumi
Imaoka, Kouki
Mochizuki, Tetsuya
Hirata, Yuzo
Fujisaki, Seiji
Takahashi, Mamoru
Nishida, Toshihiro
Sakimoto, Hideto
author_sort Fukuhara, Sotaro
collection PubMed
description INTRODUCTION: Schwannomas are neoplasms originating from Schwann cells in nerve sheath, but pancreatic schwannomas are rare. PRESENTATION OF CASE: A 59-year-old female incidentally pointed out a 2-cm-sized solid mass in the pancreas head by computed tomography (CT) which was performed for other reasons. Magnetic resonance imaging (MRI) showed a mass with hypointensity on T1-weighted images and a heterogenous hyperintensity on T2-weighted images. Magnetic resonance cholangiopancreatography (MRCP) showed no abnormal findings in the main pancreatic duct. The mass of the pancreas head showed a significantly increased uptake on fluorin-18 fluorodeoxyglucose positron emission tomography CT (FDG-PET/CT). Based on the radiological findings, a malignant potential tumor was preliminarily considered. Subtotal stomach-preserving pancreatoduodenectomy (SSSPD) was performed to make a definite diagnosis. The resected specimen showed a well-encapsulated circumscribed mass, measuring 2.0 cm, in the pancreas head. Histopathological examination revealed proliferation of spindle cells showing interlacing and palisading patterns in the tumor. The proliferating cells showed no atypia and few mitoses. Immunohistochemically, the spindle cells were positive for S-100 protein. The Ki67 labeling index was approximately 2%. Based on these findings, a diagnosis of benign schwannoma of the pancreas was made. CONCLUSION: Although pancreatic schwannoma is a rare neoplasm, it is important to take into account this tumor in the differential diagnosis of pancreatic tumors. In addition, we should be aware that FDG-PET/CT shows abnormal accumulation in a benign pancreatic schwannoma.
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spelling pubmed-54665592017-06-29 A case of pancreatic schwannoma showing increased FDG uptake on PET/CT Fukuhara, Sotaro Fukuda, Saburo Tazawa, Hirofumi Imaoka, Kouki Mochizuki, Tetsuya Hirata, Yuzo Fujisaki, Seiji Takahashi, Mamoru Nishida, Toshihiro Sakimoto, Hideto Int J Surg Case Rep Case Report INTRODUCTION: Schwannomas are neoplasms originating from Schwann cells in nerve sheath, but pancreatic schwannomas are rare. PRESENTATION OF CASE: A 59-year-old female incidentally pointed out a 2-cm-sized solid mass in the pancreas head by computed tomography (CT) which was performed for other reasons. Magnetic resonance imaging (MRI) showed a mass with hypointensity on T1-weighted images and a heterogenous hyperintensity on T2-weighted images. Magnetic resonance cholangiopancreatography (MRCP) showed no abnormal findings in the main pancreatic duct. The mass of the pancreas head showed a significantly increased uptake on fluorin-18 fluorodeoxyglucose positron emission tomography CT (FDG-PET/CT). Based on the radiological findings, a malignant potential tumor was preliminarily considered. Subtotal stomach-preserving pancreatoduodenectomy (SSSPD) was performed to make a definite diagnosis. The resected specimen showed a well-encapsulated circumscribed mass, measuring 2.0 cm, in the pancreas head. Histopathological examination revealed proliferation of spindle cells showing interlacing and palisading patterns in the tumor. The proliferating cells showed no atypia and few mitoses. Immunohistochemically, the spindle cells were positive for S-100 protein. The Ki67 labeling index was approximately 2%. Based on these findings, a diagnosis of benign schwannoma of the pancreas was made. CONCLUSION: Although pancreatic schwannoma is a rare neoplasm, it is important to take into account this tumor in the differential diagnosis of pancreatic tumors. In addition, we should be aware that FDG-PET/CT shows abnormal accumulation in a benign pancreatic schwannoma. Elsevier 2017-06-01 /pmc/articles/PMC5466559/ /pubmed/28599230 http://dx.doi.org/10.1016/j.ijscr.2017.05.031 Text en © 2017 The Author(s) http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Fukuhara, Sotaro
Fukuda, Saburo
Tazawa, Hirofumi
Imaoka, Kouki
Mochizuki, Tetsuya
Hirata, Yuzo
Fujisaki, Seiji
Takahashi, Mamoru
Nishida, Toshihiro
Sakimoto, Hideto
A case of pancreatic schwannoma showing increased FDG uptake on PET/CT
title A case of pancreatic schwannoma showing increased FDG uptake on PET/CT
title_full A case of pancreatic schwannoma showing increased FDG uptake on PET/CT
title_fullStr A case of pancreatic schwannoma showing increased FDG uptake on PET/CT
title_full_unstemmed A case of pancreatic schwannoma showing increased FDG uptake on PET/CT
title_short A case of pancreatic schwannoma showing increased FDG uptake on PET/CT
title_sort case of pancreatic schwannoma showing increased fdg uptake on pet/ct
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466559/
https://www.ncbi.nlm.nih.gov/pubmed/28599230
http://dx.doi.org/10.1016/j.ijscr.2017.05.031
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