Single Cell-Based Vector Tracing in Patients with ADA-SCID Treated with Stem Cell Gene Therapy

Clinical improvement in stem cell gene therapy (SCGT) for primary immunodeficiencies depends on the engraftment levels of genetically corrected cells, and tracing the transgene in each hematopoietic lineage is therefore extremely important in evaluating the efficacy of SCGT. We established a single...

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Detalles Bibliográficos
Autores principales: Igarashi, Yuka, Uchiyama, Toru, Minegishi, Tomoko, Takahashi, Sirirat, Watanabe, Nobuyuki, Kawai, Toshinao, Yamada, Masafumi, Ariga, Tadashi, Onodera, Masafumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466583/
https://www.ncbi.nlm.nih.gov/pubmed/28626778
http://dx.doi.org/10.1016/j.omtm.2017.05.005

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