HPW-RX40 prevents human platelet activation by attenuating cell surface protein disulfide isomerases

Protein disulfide isomerase (PDI) present at platelet surfaces has been considered to play an important role in the conformational change and activation of the integrin glycoprotein IIb/IIIa (GPIIb/IIIa) and thus enhances platelet aggregation. Growing evidences indicated that platelet surface PDI ma...

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Detalles Bibliográficos
Autores principales: Kung, Po-Hsiung, Hsieh, Pei-Wen, Lin, Ying-Ting, Lee, Jia-Hau, Chen, I-Hua, Wu, Chin-Chung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466588/
https://www.ncbi.nlm.nih.gov/pubmed/28600983
http://dx.doi.org/10.1016/j.redox.2017.05.019

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