Cargando…
Attenuation of opioid tolerance by ET(B) receptor agonist, IRL-1620, is independent of an accompanied decrease in nerve growth factor in mice
AIM: ET(A) receptor antagonists reverse opioid tolerance but the involvement of ET(B) receptors is unknown. In morphine or oxycodone tolerant mice we investigated (1) the effect of ET(B) receptor agonist, IRL-1620, on analgesic tolerance; (2) changes in expression of the brain ET(A) and ET(B) recept...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2017
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466593/ https://www.ncbi.nlm.nih.gov/pubmed/28626808 http://dx.doi.org/10.1016/j.heliyon.2017.e00317 |