Conserved amino acid networks modulate discrete functional properties in an enzyme superfamily

In this work, we applied the sequence-based statistical coupling analysis approach to characterize conserved amino acid networks important for biochemical function in the pancreatic-type ribonuclease (ptRNase) superfamily. This superfamily-wide analysis indicates a decomposition of the RNase tertiar...

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Detalles Bibliográficos
Autores principales: Narayanan, Chitra, Gagné, Donald, Reynolds, Kimberly A., Doucet, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466627/
https://www.ncbi.nlm.nih.gov/pubmed/28600532
http://dx.doi.org/10.1038/s41598-017-03298-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466627/
https://www.ncbi.nlm.nih.gov/pubmed/28600532
http://dx.doi.org/10.1038/s41598-017-03298-4

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