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Malnutrition-sarcopenia syndrome predicts mortality in hospitalized older patients
A new term, malnutrition-sarcopenia syndrome (MSS), was recently coined to describe the clinical presentation of both malnutrition and sarcopenia. The aim of this study was to investigate the association between MSS and long-term mortality in older inpatients. We conducted a prospective study in acu...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466644/ https://www.ncbi.nlm.nih.gov/pubmed/28600505 http://dx.doi.org/10.1038/s41598-017-03388-3 |
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author | Hu, Xiaoyi Zhang, Lei Wang, Haozhong Hao, Qiukui Dong, Birong Yang, Ming |
author_facet | Hu, Xiaoyi Zhang, Lei Wang, Haozhong Hao, Qiukui Dong, Birong Yang, Ming |
author_sort | Hu, Xiaoyi |
collection | PubMed |
description | A new term, malnutrition-sarcopenia syndrome (MSS), was recently coined to describe the clinical presentation of both malnutrition and sarcopenia. The aim of this study was to investigate the association between MSS and long-term mortality in older inpatients. We conducted a prospective study in acute geriatric wards of two local hospitals in China. Muscle mass and malnutrition were estimated by anthropometric measures and the Mini Nutritional Assessment (MNA). Of the 453 participants, 14 (3.1%) had sarcopenia with normal nutrition, 139 (30.7%) had malnutrition risk without sarcopenia, 48 (10.6%) had malnutrition risk with sarcopenia, 25 (5.5%) had malnutrition without sarcopenia, and 22 (4.9%) had MSS at baseline. Compared with non-sarcopenic subjects with normal nutrition, subjects with MSS and subjects with malnutrition risk and sarcopenia were more than four times more likely to die (hazard ratio [HR], 4.78; 95% confidence interval [CI], 2.09–10.97; and HR, 4.25; 95% CI, 2.22–8.12, respectively); non-sarcopenic subjects with malnutrition risk were more than two times more likely to die (HR, 2.41; 95% CI, 1.32–4.39). In conclusion, MSS may serve as a prognostic factor in the management of hospitalized older patients. |
format | Online Article Text |
id | pubmed-5466644 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-54666442017-06-14 Malnutrition-sarcopenia syndrome predicts mortality in hospitalized older patients Hu, Xiaoyi Zhang, Lei Wang, Haozhong Hao, Qiukui Dong, Birong Yang, Ming Sci Rep Article A new term, malnutrition-sarcopenia syndrome (MSS), was recently coined to describe the clinical presentation of both malnutrition and sarcopenia. The aim of this study was to investigate the association between MSS and long-term mortality in older inpatients. We conducted a prospective study in acute geriatric wards of two local hospitals in China. Muscle mass and malnutrition were estimated by anthropometric measures and the Mini Nutritional Assessment (MNA). Of the 453 participants, 14 (3.1%) had sarcopenia with normal nutrition, 139 (30.7%) had malnutrition risk without sarcopenia, 48 (10.6%) had malnutrition risk with sarcopenia, 25 (5.5%) had malnutrition without sarcopenia, and 22 (4.9%) had MSS at baseline. Compared with non-sarcopenic subjects with normal nutrition, subjects with MSS and subjects with malnutrition risk and sarcopenia were more than four times more likely to die (hazard ratio [HR], 4.78; 95% confidence interval [CI], 2.09–10.97; and HR, 4.25; 95% CI, 2.22–8.12, respectively); non-sarcopenic subjects with malnutrition risk were more than two times more likely to die (HR, 2.41; 95% CI, 1.32–4.39). In conclusion, MSS may serve as a prognostic factor in the management of hospitalized older patients. Nature Publishing Group UK 2017-06-09 /pmc/articles/PMC5466644/ /pubmed/28600505 http://dx.doi.org/10.1038/s41598-017-03388-3 Text en © The Author(s) 2017 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Hu, Xiaoyi Zhang, Lei Wang, Haozhong Hao, Qiukui Dong, Birong Yang, Ming Malnutrition-sarcopenia syndrome predicts mortality in hospitalized older patients |
title | Malnutrition-sarcopenia syndrome predicts mortality in hospitalized older patients |
title_full | Malnutrition-sarcopenia syndrome predicts mortality in hospitalized older patients |
title_fullStr | Malnutrition-sarcopenia syndrome predicts mortality in hospitalized older patients |
title_full_unstemmed | Malnutrition-sarcopenia syndrome predicts mortality in hospitalized older patients |
title_short | Malnutrition-sarcopenia syndrome predicts mortality in hospitalized older patients |
title_sort | malnutrition-sarcopenia syndrome predicts mortality in hospitalized older patients |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466644/ https://www.ncbi.nlm.nih.gov/pubmed/28600505 http://dx.doi.org/10.1038/s41598-017-03388-3 |
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