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Dose-dependent effects of intravenous methoxamine infusion during hip-joint replacement surgery on postoperative cognitive dysfunction and blood TNF-α level in elderly patients: a randomized controlled trial

BACKGROUND: Postoperative cognitive dysfunction (POCD), common in elderly patients, is thought to be closely associated with intraoperative instability of hemodynamics and excessive excretion of tumor necrosis factor-α (TNF-α). Methoxamine is a blood-pressure increasing drug commonly used for mainta...

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Detalles Bibliográficos
Autores principales: Sun, Shenghui, Sun, Defeng, Yang, Lin, Han, Jun, Liu, Ruochuan, Wang, Lijie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466783/
https://www.ncbi.nlm.nih.gov/pubmed/28599629
http://dx.doi.org/10.1186/s12871-017-0367-6

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