Indoxyl Sulfate Affects Glial Function Increasing Oxidative Stress and Neuroinflammation in Chronic Kidney Disease: Interaction between Astrocytes and Microglia

Indoxyl sulfate (IS) is a protein-bound uremic toxin resulting from the metabolism of dietary tryptophan which accumulates in patients with impaired renal function, such as chronic kidney disease (CKD). IS is a well-known nephrovascular toxin but little is known about its effects on central nervous...

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Detalles Bibliográficos
Autores principales: Adesso, Simona, Magnus, Tim, Cuzzocrea, Salvatore, Campolo, Michela, Rissiek, Björn, Paciello, Orlando, Autore, Giuseppina, Pinto, Aldo, Marzocco, Stefania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466960/
https://www.ncbi.nlm.nih.gov/pubmed/28659803
http://dx.doi.org/10.3389/fphar.2017.00370

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466960/
https://www.ncbi.nlm.nih.gov/pubmed/28659803
http://dx.doi.org/10.3389/fphar.2017.00370

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