ER stress protein AGR2 precedes and is involved in the regulation of pancreatic cancer initiation

The mechanisms of initiation of pancreatic ductal adenocarcinoma (PDAC) are still largely unknown. In the present study, we analysed the role of anterior gradient-2 (AGR2) in the earliest stages of pancreatic neoplasia. Immunohistochemical analysis of chronic pancreatitis (CP) and peritumoral areas...

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Detalles Bibliográficos
Autores principales: Dumartin, L, Alrawashdeh, W, Trabulo, S M, Radon, T P, Steiger, K, Feakins, R M, di Magliano, M P, Heeschen, C, Esposito, I, Lemoine, N R, Crnogorac-Jurcevic, T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467015/
https://www.ncbi.nlm.nih.gov/pubmed/27941872
http://dx.doi.org/10.1038/onc.2016.459

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