Thymic large cell neuroendocrine carcinoma – a rare and aggressive tumor: a case report

BACKGROUND: Neuroendocrine tumors are a large group of tumors with a wide spectrum of behavior, affecting mainly the digestive system and the lung. The thymus is very rarely affected. CASE PRESENTATION: A 28-year-old Arab woman presented with chronic chest pain and dyspnea. A computed tomography sca...

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Autores principales: Boubacar, Efared, Atsame-Ebang, Gabrielle, Rabiou, Sani, Fatimazahra, Ammor, Mazti, Asmae, Sidibé, Ibrahim S., Tahiri, Layla, Hammas, Nawal, Yassine, Ouadnouni, Mohamed, Smahi, Laila, Chbani, Hinde, El Fatemi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467048/
https://www.ncbi.nlm.nih.gov/pubmed/28602157
http://dx.doi.org/10.1186/s13256-017-1331-2
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author Boubacar, Efared
Atsame-Ebang, Gabrielle
Rabiou, Sani
Fatimazahra, Ammor
Mazti, Asmae
Sidibé, Ibrahim S.
Tahiri, Layla
Hammas, Nawal
Yassine, Ouadnouni
Mohamed, Smahi
Laila, Chbani
Hinde, El Fatemi
author_facet Boubacar, Efared
Atsame-Ebang, Gabrielle
Rabiou, Sani
Fatimazahra, Ammor
Mazti, Asmae
Sidibé, Ibrahim S.
Tahiri, Layla
Hammas, Nawal
Yassine, Ouadnouni
Mohamed, Smahi
Laila, Chbani
Hinde, El Fatemi
author_sort Boubacar, Efared
collection PubMed
description BACKGROUND: Neuroendocrine tumors are a large group of tumors with a wide spectrum of behavior, affecting mainly the digestive system and the lung. The thymus is very rarely affected. CASE PRESENTATION: A 28-year-old Arab woman presented with chronic chest pain and dyspnea. A computed tomography scan showed a huge anterior mediastinal mass invading neighboring structures. A mediastinotomy was performed with biopsies of the mass. Pathological findings were consistent with a thymic large cell neuroendocrine carcinoma. CONCLUSIONS: The occurrence of a large cell neuroendocrine carcinoma in the thymus, especially in young people, is extremely rare. In this current report, we discuss the clinicopathological issues of this rare tumor according to recent literature data.
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spelling pubmed-54670482017-06-14 Thymic large cell neuroendocrine carcinoma – a rare and aggressive tumor: a case report Boubacar, Efared Atsame-Ebang, Gabrielle Rabiou, Sani Fatimazahra, Ammor Mazti, Asmae Sidibé, Ibrahim S. Tahiri, Layla Hammas, Nawal Yassine, Ouadnouni Mohamed, Smahi Laila, Chbani Hinde, El Fatemi J Med Case Rep Case Report BACKGROUND: Neuroendocrine tumors are a large group of tumors with a wide spectrum of behavior, affecting mainly the digestive system and the lung. The thymus is very rarely affected. CASE PRESENTATION: A 28-year-old Arab woman presented with chronic chest pain and dyspnea. A computed tomography scan showed a huge anterior mediastinal mass invading neighboring structures. A mediastinotomy was performed with biopsies of the mass. Pathological findings were consistent with a thymic large cell neuroendocrine carcinoma. CONCLUSIONS: The occurrence of a large cell neuroendocrine carcinoma in the thymus, especially in young people, is extremely rare. In this current report, we discuss the clinicopathological issues of this rare tumor according to recent literature data. BioMed Central 2017-06-12 /pmc/articles/PMC5467048/ /pubmed/28602157 http://dx.doi.org/10.1186/s13256-017-1331-2 Text en © The Author(s). 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Boubacar, Efared
Atsame-Ebang, Gabrielle
Rabiou, Sani
Fatimazahra, Ammor
Mazti, Asmae
Sidibé, Ibrahim S.
Tahiri, Layla
Hammas, Nawal
Yassine, Ouadnouni
Mohamed, Smahi
Laila, Chbani
Hinde, El Fatemi
Thymic large cell neuroendocrine carcinoma – a rare and aggressive tumor: a case report
title Thymic large cell neuroendocrine carcinoma – a rare and aggressive tumor: a case report
title_full Thymic large cell neuroendocrine carcinoma – a rare and aggressive tumor: a case report
title_fullStr Thymic large cell neuroendocrine carcinoma – a rare and aggressive tumor: a case report
title_full_unstemmed Thymic large cell neuroendocrine carcinoma – a rare and aggressive tumor: a case report
title_short Thymic large cell neuroendocrine carcinoma – a rare and aggressive tumor: a case report
title_sort thymic large cell neuroendocrine carcinoma – a rare and aggressive tumor: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467048/
https://www.ncbi.nlm.nih.gov/pubmed/28602157
http://dx.doi.org/10.1186/s13256-017-1331-2
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