Sequence variants in ARHGAP15, COLQ and FAM155A associate with diverticular disease and diverticulitis

Diverticular disease is characterized by pouches (that is, diverticulae) due to weakness in the bowel wall, which can become infected and inflamed causing diverticulitis, with potentially severe complications. Here, we test 32.4 million sequence variants identified through whole-genome sequencing (W...

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Detalles Bibliográficos
Autores principales: Sigurdsson, Snaevar, Alexandersson, Kristjan F., Sulem, Patrick, Feenstra, Bjarke, Gudmundsdottir, Steinunn, Halldorsson, Gisli H., Olafsson, Sigurgeir, Sigurdsson, Asgeir, Rafnar, Thorunn, Thorgeirsson, Thorgeir, Sørensen, Erik, Nordholm-Carstensen, Andreas, Burcharth, Jakob, Andersen, Jens, Jørgensen, Henrik Stig, Possfelt-Møller, Emma, Ullum, Henrik, Thorleifsson, Gudmar, Masson, Gisli, Thorsteinsdottir, Unnur, Melbye, Mads, Gudbjartsson, Daniel F., Stefansson, Tryggvi, Jonsdottir, Ingileif, Stefansson, Kari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467205/
https://www.ncbi.nlm.nih.gov/pubmed/28585551
http://dx.doi.org/10.1038/ncomms15789

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