The CaMKII holoenzyme structure in activation-competent conformations

The Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) assembles into large 12-meric holoenzymes, which is thought to enable regulatory processes required for synaptic plasticity underlying learning, memory and cognition. Here we used single particle electron microscopy (EM) to determine a pseud...

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Detalles Bibliográficos
Autores principales: Myers, Janette B., Zaegel, Vincent, Coultrap, Steven J., Miller, Adam P., Bayer, K. Ulrich, Reichow, Steve L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467236/
https://www.ncbi.nlm.nih.gov/pubmed/28589927
http://dx.doi.org/10.1038/ncomms15742

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