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Sortilin-Related Receptor Expression in Human Neural Stem Cells Derived from Alzheimer's Disease Patients Carrying the APOE Epsilon 4 Allele

Alzheimer's disease (AD) is the most common form of dementia in the elderly; important risk factors are old age and inheritance of the apolipoprotein E4 (APOE4) allele. Changes in amyloid precursor protein (APP) binding, trafficking, and sorting may be important AD causative factors. Secretase-...

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Detalles Bibliográficos
Autores principales:	Zollo, Alen, Allen, Zoe, Rasmussen, Helle F., Iannuzzi, Filomena, Shi, Yichen, Larsen, Agnete, Maier, Thorsten J., Matrone, Carmela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467336/ https://www.ncbi.nlm.nih.gov/pubmed/28634550 http://dx.doi.org/10.1155/2017/1892612

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