The Impact of Aging on Brain Pituitary Adenylate Cyclase Activating Polypeptide, Pathology and Cognition in Mice and Rhesus Macaques

Pituitary adenylate cyclase activating polypeptide (PACAP) is associated with Alzheimer’s disease (AD), but its age-related effects are unknown. We chose the rhesus macaque due to its closeness to human anatomy and physiology. We examined four variables: aging, cognitive performance, amyloid plaques...

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Detalles Bibliográficos
Autores principales: Han, Pengcheng, Nielsen, Megan, Song, Melissa, Yin, Junxiang, Permenter, Michele R., Vogt, Julie A., Engle, James R., Dugger, Brittany N., Beach, Thomas G., Barnes, Carol A., Shi, Jiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467357/
https://www.ncbi.nlm.nih.gov/pubmed/28659785
http://dx.doi.org/10.3389/fnagi.2017.00180

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