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Wortmannin Attenuates Seizure-Induced Hyperactive PI3K/Akt/mTOR Signaling, Impaired Memory, and Spine Dysmorphology in Rats

Numerous studies have shown epilepsy-associated cognitive deficits, but less is known about the effects of one single generalized seizure. Recent studies demonstrate that a single, self-limited seizure can result in memory deficits and induces hyperactive phosphoinositide 3-kinase/Akt (protein kinas...

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Detalles Bibliográficos
Autores principales:	Carter, Angela N., Born, Heather A., Levine, Amber T., Dao, An T., Zhao, Amanda J., Lee, Wai L., Anderson, Anne E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Society for Neuroscience 2017
Materias:	New Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467399/ https://www.ncbi.nlm.nih.gov/pubmed/28612047 http://dx.doi.org/10.1523/ENEURO.0354-16.2017

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