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MAP4K4 is a novel MAPK/ERK pathway regulator required for lung adenocarcinoma maintenance
About 76% of patients with lung adenocarcinoma harbor activating mutations in the receptor tyrosine kinase (RTK)/RAS/RAF pathways, leading to aberrant activation of the mitogen‐activated protein kinase (MAPK) pathways particularly the MAPK/ERK pathway. However, many lung adenocarcinomas lacking thes...
Autores principales: | Gao, Xuan, Chen, Guangming, Gao, Chenxi, Zhang, Dennis Han, Kuan, Shih‐Fan, Stabile, Laura P., Liu, Guoxiang, Hu, Jing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467491/ https://www.ncbi.nlm.nih.gov/pubmed/28306189 http://dx.doi.org/10.1002/1878-0261.12055 |
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