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USP22 mediates the multidrug resistance of hepatocellular carcinoma via the SIRT1/AKT/MRP1 signaling pathway

Drug treatments for hepatocellular carcinoma (HCC) often fail because of multidrug resistance (MDR). The mechanisms of MDR are complex but cancer stem cells (CSCs), which are able to self‐renew and differentiate, have recently been shown to be involved. The deubiquitinating enzyme ubiquitin‐specific...

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Detalles Bibliográficos
Autores principales:	Ling, Sunbin, Li, Jie, Shan, Qiaonan, Dai, Haojiang, Lu, Di, Wen, Xue, Song, Penghong, Xie, Haiyang, Zhou, Lin, Liu, Jimin, Xu, Xiao, Zheng, Shusen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2017
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467492/ https://www.ncbi.nlm.nih.gov/pubmed/28417539 http://dx.doi.org/10.1002/1878-0261.12067

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