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FEN1 promotes tumor progression and confers cisplatin resistance in non‐small‐cell lung cancer

Lung cancer is one of the leading causes of cancer mortality worldwide. The therapeutic effect of chemotherapy is limited due to the resistance of cancer cells, which remains a challenge in cancer therapeutics. In this work, we found that flap endonuclease 1 (FEN1) is overexpressed in lung cancer ce...

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Detalles Bibliográficos
Autores principales: He, Lingfeng, Luo, Libo, Zhu, Hong, Yang, Huan, Zhang, Yilan, Wu, Huan, Sun, Hongfang, Jiang, Feng, Kathera, Chandra S., Liu, Lingjie, Zhuang, Ziheng, Chen, Haoyan, Pan, Feiyan, Hu, Zhigang, Zhang, Jing, Guo, Zhigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467497/
https://www.ncbi.nlm.nih.gov/pubmed/28371273
http://dx.doi.org/10.1002/1878-0261.12058