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Tumor RAS Gene Expression Levels Are Influenced by the Mutational Status of RAS Genes and Both Upstream and Downstream RAS Pathway Genes
The 3 human RAS genes play pivotal roles regulating proliferation, differentiation, and survival in normal cells and become mutated in 15% to 20% of all human tumors and amplified in many others. In this report, we examined data from The Cancer Genome Atlas to investigate the relationship between RA...
Autores principales: | Stephens, Robert M, Yi, Ming, Kessing, Bailey, Nissley, Dwight V, McCormick, Frank |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467702/ https://www.ncbi.nlm.nih.gov/pubmed/28634423 http://dx.doi.org/10.1177/1176935117711944 |
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