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Temperature sensitive liposomes combined with thermal ablation: Effects of duration and timing of heating in mathematical models and in vivo

BACKGROUND: Temperature sensitive liposomes (TSL) are nanoparticles that rapidly release the contained drug at hyperthermic temperatures, typically above ~40°C. TSL have been combined with various heating modalities, but there is no consensus on required hyperthermia duration or ideal timing of heat...

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Detalles Bibliográficos
Autores principales: Rossmann, Christian, McCrackin, M. A., Armeson, Kent E., Haemmerich, Dieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467840/
https://www.ncbi.nlm.nih.gov/pubmed/28604815
http://dx.doi.org/10.1371/journal.pone.0179131