Leptomeningeal Carcinomatosis in Recurrent Non-Small Cell Lung Cancer: A Case Report and Review of Current Treatment Modalities

Leptomeningeal carcinomatosis (LC) is an uncommon sequelae of non-small cell lung cancer. The treatment modalities for LC have historically been limited with an overall poor prognosis. This case report outlines a 76-year-old female who presented with recurrence of non-small cell lung cancer as LC. L...

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Detalles Bibliográficos
Autores principales: Abbasi, Saqib, Moussaly, Elias, Atallah, Jean P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2017
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467982/
https://www.ncbi.nlm.nih.gov/pubmed/28620571
http://dx.doi.org/10.7759/cureus.1242
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author Abbasi, Saqib
Moussaly, Elias
Atallah, Jean P
author_facet Abbasi, Saqib
Moussaly, Elias
Atallah, Jean P
author_sort Abbasi, Saqib
collection PubMed
description Leptomeningeal carcinomatosis (LC) is an uncommon sequelae of non-small cell lung cancer. The treatment modalities for LC have historically been limited with an overall poor prognosis. This case report outlines a 76-year-old female who presented with recurrence of non-small cell lung cancer as LC. LC is difficult to treat, and options include radiation, chemotherapy (systemic and intrathecal), as well as targeted therapies. This case outlines a unique approach and reviews the current literature on the effectiveness of these options in non-small cell lung cancer.
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spelling pubmed-54679822017-06-15 Leptomeningeal Carcinomatosis in Recurrent Non-Small Cell Lung Cancer: A Case Report and Review of Current Treatment Modalities Abbasi, Saqib Moussaly, Elias Atallah, Jean P Cureus Oncology Leptomeningeal carcinomatosis (LC) is an uncommon sequelae of non-small cell lung cancer. The treatment modalities for LC have historically been limited with an overall poor prognosis. This case report outlines a 76-year-old female who presented with recurrence of non-small cell lung cancer as LC. LC is difficult to treat, and options include radiation, chemotherapy (systemic and intrathecal), as well as targeted therapies. This case outlines a unique approach and reviews the current literature on the effectiveness of these options in non-small cell lung cancer. Cureus 2017-05-12 /pmc/articles/PMC5467982/ /pubmed/28620571 http://dx.doi.org/10.7759/cureus.1242 Text en Copyright © 2017, Abbasi et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Oncology
Abbasi, Saqib
Moussaly, Elias
Atallah, Jean P
Leptomeningeal Carcinomatosis in Recurrent Non-Small Cell Lung Cancer: A Case Report and Review of Current Treatment Modalities
title Leptomeningeal Carcinomatosis in Recurrent Non-Small Cell Lung Cancer: A Case Report and Review of Current Treatment Modalities
title_full Leptomeningeal Carcinomatosis in Recurrent Non-Small Cell Lung Cancer: A Case Report and Review of Current Treatment Modalities
title_fullStr Leptomeningeal Carcinomatosis in Recurrent Non-Small Cell Lung Cancer: A Case Report and Review of Current Treatment Modalities
title_full_unstemmed Leptomeningeal Carcinomatosis in Recurrent Non-Small Cell Lung Cancer: A Case Report and Review of Current Treatment Modalities
title_short Leptomeningeal Carcinomatosis in Recurrent Non-Small Cell Lung Cancer: A Case Report and Review of Current Treatment Modalities
title_sort leptomeningeal carcinomatosis in recurrent non-small cell lung cancer: a case report and review of current treatment modalities
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467982/
https://www.ncbi.nlm.nih.gov/pubmed/28620571
http://dx.doi.org/10.7759/cureus.1242
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AT atallahjeanp leptomeningealcarcinomatosisinrecurrentnonsmallcelllungcanceracasereportandreviewofcurrenttreatmentmodalities

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