IGF-1 mediated Neurogenesis Involves a Novel RIT1/Akt/Sox2 Cascade

Insulin-like growth factor 1 (IGF-1) is known to have diverse effects on brain structure and function, including the promotion of stem cell proliferation and neurogenesis in the adult dentate gyrus. However, the intracellular pathways downstream of the IGF-1 receptor that contribute to these diverse...

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Detalles Bibliográficos
Autores principales: Mir, Sajad, Cai, Weikang, Carlson, Shaun W., Saatman, Kathryn E., Andres, Douglas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5468318/
https://www.ncbi.nlm.nih.gov/pubmed/28607354
http://dx.doi.org/10.1038/s41598-017-03641-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5468318/
https://www.ncbi.nlm.nih.gov/pubmed/28607354
http://dx.doi.org/10.1038/s41598-017-03641-9

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