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IGF-1 mediated Neurogenesis Involves a Novel RIT1/Akt/Sox2 Cascade
Insulin-like growth factor 1 (IGF-1) is known to have diverse effects on brain structure and function, including the promotion of stem cell proliferation and neurogenesis in the adult dentate gyrus. However, the intracellular pathways downstream of the IGF-1 receptor that contribute to these diverse...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5468318/ https://www.ncbi.nlm.nih.gov/pubmed/28607354 http://dx.doi.org/10.1038/s41598-017-03641-9 |